Lassa fever case found in New Jersey

first_img Lassa fever is rarely found outside of West Africa. But the case study published in the Centers for Disease Control and Prevention (CDC) publication points out that the ease of international travel has also made microbes mobile. MMWR recommended that clinicians consider both common and uncommon diseases when evaluating patients who have traveled from Africa. Clinical histories must uncover travel to regions with uncommon endemic diseases, and lab work must be done quickly, the report added. Rats in the genus Mastomys, which live throughout West Africa, host Lassa. The virus can be spread when people kill and eat the rats, when the rats contaminate poorly stored human food, when dust containing virus shed in urine or feces becomes airborne, and through people’s cuts and sores. Lassa fever can also spread through contact with the fluids of a human victim. It kills about 5,000 people a year, CDC said. Estimates place the number of Lassa infections between 100,000 to 300,000 annually, with the caveat that regional surveillance is spotty, according to the report. Seventeen of the 19 plane passengers were from the United Kingdom and two were Americans. Only three passengers could not be contacted. All the contacted passengers were healthy and had not suffered fevers within the 21-day incubation period for Lassa, MMWR reported. Oct 6, 2004 (CIDRAP News) – The first US case of Lassa fever since 1989 is a reminder that physicians need to consider exotic diseases when making diagnoses, noted the Oct 1 edition of Morbidity and Mortality Weekly Report (MMWR). His death and diagnosis prompted an intensive search to find people with whom he had contact while ill. Multiple criteria were used to determine if that contact was high- or low-risk. Hours later the 38-year-old man was hospitalized in Trenton, N.J., for fever, chills, sore throat, diarrhea, and back pain. His temperature was 103.6°F. Physicians initially suspected malaria and typhoid fever, and treated him with antimalarials and antibiotics. Of the 188 people who had contact with the man during his likely infectious period, five were classified as high-risk and 183 as low-risk. Those at risk included family members; nurses, physicians and lab workers at the Trenton hospital; lab workers at commercial laboratories in California and Virginia; and 19 fellow airplane passengers. A Liberian businessman who lived in New Jersey but commuted to farms in Liberia and Sierra Leone fell ill during the final days of a 5-month stint in Africa in August, CDC reports said. Two days later he flew from Freetown, Sierra Leone, through London to Newark, N.J. He rode a train on the last leg of his journey. A few hours after that consultation on Aug 28, the patient died without receiving the ribavirin. Serum antigen detection, reverse transcriptase-polymerase chain reaction, and other tests confirmed he died of Lassa fever, only the 20th imported case to have been noted worldwide, MMWR said. The children of some at-risk patients were kept from school until the incubation period expired on Sep 18, MMWR said. No contacts contracted Lassa-like symptoms.CDC describes Lassa fever as an acute viral illness endemic to West Africa. It is named for the Nigerian town where two missionary nurses died in 1969. The zoonotic virus from the family Arenaviridae is mild or asymptomatic in about 80% of human victims. The other 20%, however, develop a severe, multisymptom disease that can include shock, hemorrhage, seizures, and death. Outbreaks can prompt case-fatality rates as high as 50%. Despite treatment, the man’s condition worsened. By his fourth day in the hospital, he was in respiratory distress. Doctors intubated and ventilated him, and reconsidered the initial diagnoses. This time yellow fever and Lassa fever rose to the top of the list, the report said. After notifying state health officials and consulting CDC, doctors arranged to give the patient ribavirin intravenously, under an investigational new drug protocol. CDC. Imported Lassa fever: New Jersey, 2004. MMWR 2004 Oct 1;53(38):894-7 [Full text]last_img read more

Dodgers beat Angels in their exhibition finale behind Chris Taylor’s three-run homer

first_img“I’m just trying to stay calm in the box and work on my breathing and trying not to have my legs shake as much when I’m out there,” McKinstry said afterward. “It’s kind of surreal. It’s awesome, every day I come out here and every day is another awesome day at Dodger Stadium.”It was the final tune-up for the Dodgers before Thursday’s season opener at home against the San Francisco Giants to open a four-game series, in which Clayton Kershaw will go up against the Giants’ Johnny Cueto.“It’s very gratifying,” Dodgers manager Dave Roberts of being ready for opening day. “You don’t have to look too far back to think that this day and getting so close to opening day was ever going to happen. We got through this and guys are feeling good and healthy and have opening day to look forward too.”The Angels have their final exhibition game at home against San Diego on Wednesday, and then hit the road for a three-game series in Oakland, beginning with their season opener on Friday against the A’s.The Angels and Dodgers’ two biggest acquisitions of the off-season did not play. Dodgers outfielder Mookie Betts, who arrived in a trade from the Boston Red Sox, took the night off after hitting a three-run homer in Monday’s 12-1 rout of Arizona.Third baseman Anthony Rendon, who signed with the Angels after winning a World Series with the Washington Nationals, did not play either. He has oblique tightness caused by a swing in an intrasquad game and his status is in doubt for opening day.“He’s still day to day and still a little sore,” Angels manager Joe Maddon said. “We don’t anticipate him playing (Wednesday) and have to make a decision relatively soon and we will get down into hunker down mode and try to figure this out going into the weekend against Oakland.”Maddon was asked if Rendon might start the season on injured reserve.“I don’t know that,” Maddon said. “I just know that he’s not well yet and we’re talking to trainers to see what they think and then we will go forward and conclude.”The Angels’ Felix Pena started and went just two innings, allowing the two-run double to Hernandez. But he otherwise felt well and is still awaiting a decision from Maddon on whether he will be a starter or come out of the bullpen during the season.“Not yet,” Pena said if Maddon had defined his role. “I’m not sure what role I’ll be in.”But if you ask the 30-year-old in his third season with the Angels after previously being with the Chicago Cubs, he’s ready to start.“Of course,” Pena said., “I’m ready to be a starter and pitch five or six innings. I feel good mentally. I’m very different now. I am a man, not a kid anymore and a lot more mature.”The Dodgers’ 22-year-old Josiah Gray went 3 2/3 innings, allowing three hits and two runs with three strikeouts.TEHERAN FEELING GOODBefore Tuesday’s game, Angels pitcher Julio Teheran, who tested positive for COVID 19 two days before he was supposed to report for summer camp, said he is feeling much better now and looking forward to the season.“I have been staying active, taking care of myself, I know how to do this. I’m a week behind, but excited to be back,” Teheran said. PreviousLos Angeles Angels’ Shohei Ohtani, left, drops his bat as he pops out while Los Angeles Dodgers starting pitcher Josiah Gray watches during the first inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Dodgers’ Chris Taylor, right, hits a three-run home run as Los Angeles Angels pitcher Jaime Barria, left, watches along with catcher Max Stassi and home plate umpire D.J. Reyburn during the third inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Dodgers shortstop Corey Seager can’t reach a ball hit for a single by Los Angeles Angels’ Max Stassi during the second inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill) SoundThe gallery will resume insecondsThe Los Angeles Dodgers play the Los Angeles Angels at sunset during the fifth inning of a preseason baseball game, Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Angels’ Shohei Ohtani, left, walks back to the dugout followed by a bat boy after popping out in the first inning of a preseason baseball game against the Los Angeles Dodgers, Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Angels’ Shohei Ohtani takes his helmet off after popping out during the first inning of a preseason baseball game against the Los Angeles Dodgers, Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Angels’ Shohei Ohtani, right, walks back to the dugout after striking out to end the inning as Los Angeles Dodgers catcher Austin Barnes, center, walks away and home plate umpire D.J. Reyburn stands at the plate during the third inning of a preseason baseball game, Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Angels relief pitcher Felix Peña throws to the plate during the first inning of a preseason baseball game against the Los Angeles Dodgers Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Dodgers’ Chris Taylor, center, drops his bat as he hits a three-run home run while Los Angeles Angels pitcher Jaime Barria, left, watches along with catcher Max Stassi during the third inning of a preseason baseball game, Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Angels’ Tommy La Stella, right, is congratulated by Albert Pujols, left, after hitting a solo home run as Los Angeles Dodgers catcher Austin Barnes kneels at the plate during the second inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Angels’ Tommy La Stella, left, drops his bat as he hits a solo home run as Los Angeles Dodgers starting pitcher Josiah Gray watches during the second inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Dodgers right fielder Joc Pederson, left, picks up his hat as members of the Los Angeles Angels laugh in the bullpen after he was able to catch a ball hit for a solo home run by Tommy La Stella during the second inning of a preseason baseball game, Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Dodgers’ Chris Taylor, right, is congratulated by A.J. Pollock, left, and Justin Turner, second from left, after hitting a three-run home run as Los Angeles Angels catcher Max Stassi stands at the plate during the third inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)A bat boy runs back to the dugout with a bat as Los Angeles Angels’ Max Stassi second from left, walks up to the plate past Los Angeles Dodgers catcher Austin Barnes, left, during the second inning of a preseason baseball game, Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Angels’ Shohei Ohtani, second left, pops out while Los Angeles Dodgers starting pitcher Josiah Gray, left, watches along with catcher Austin Barnes, right, and home plate umpire D.J. Reyburn during the first inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Dodgers third baseman Justin Turner, right, makes a catch on a ball hit by Los Angeles Angels’ Justin Upton as shortstop Corey Seager watches during the first inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Dodgers starting pitcher Josiah Gray throws back to first to check Los Angeles Angels’ Mike Trout during the first inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Angels’ Shohei Ohtani, left, drops his bat as he pops out while Los Angeles Dodgers starting pitcher Josiah Gray watches during the first inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)Los Angeles Dodgers’ Chris Taylor, right, hits a three-run home run as Los Angeles Angels pitcher Jaime Barria, left, watches along with catcher Max Stassi and home plate umpire D.J. Reyburn during the third inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)NextShow Caption1 of 17Los Angeles Dodgers’ Chris Taylor, right, hits a three-run home run as Los Angeles Angels pitcher Jaime Barria, left, watches along with catcher Max Stassi and home plate umpire D.J. Reyburn during the third inning of a preseason baseball game Tuesday, July 21, 2020, in Los Angeles. (AP Photo/Mark J. Terrill)ExpandThe Dodgers won their only three exhibition games before Major League Baseball’s COVID-19 shortened 60-game season begins later this week without fans in ballparks.There will be plenty of time for the Dodgers and Angels to mix it up when they meet six times during the season, and they were entertaining in their only exhibition meeting on Tuesday, with the Dodgers holding on for a 6-4 victory behind a three-run homer from Chris Taylor in the third inning, his second homer in two nights, and with help from Kike Hernandez, who doubled home two runs in the second inning.The Angels got a solo homer from Tommy La Stella in the second inning, and trailing 5-2 in the seventh, added two more home runs from Albert Pujols and Brian Goodwin to pull within a run.But the Dodgers’ Zach McKinstry provided some breathing room and furthered his case to make the Dodgers’ roster, hitting a home run in the eighth inning.center_img Newsroom GuidelinesNews TipsContact UsReport an Errorlast_img read more